Definition:
Mesembrine is the primary active alkaloid found in the kanna plant (Sceletium tortuosum). It is largely responsible for the mood-enhancing and anxiolytic effects users report
Further reading – What is kanna?
What it does:
Mesembrine is known to affect the brain through multiple pathways:
- Serotonin Reuptake Inhibition (SRI): Increases the amount of serotonin in the brain by preventing its reabsorption.
- PDE-4 Inhibition: Can reduce inflammation and enhance mood/cog