Definition:
Mesembrenone is one of the primary alkaloids found in Sceletium tortuosum (kanna). It is known for its ability to inhibit serotonin reuptake (SRI) and phosphodiesterase-4 (PDE-4), making it a key contributor to kanna’s mood-elevating and calming effects. Compared to mesembrine, mesembrenone is generally considered less stimulating and more balanced in its effects.
Why it matters:
Mesembrenone is the dominant alkaloid in certain standardized kanna extracts like Zembrin. If you’re looking for a kanna product that offers emotional support without overstimulation, a mesembrenone-forward extract might be your best choice.
Check out Where To Buy Kanna Near Me for help choosing the right product.
Further reading:
See the full What is Kanna guide.
Related Terms:
