Alkaloid

Our recommended vendorSceletium tortuosum
Ultrakanna KannaDroplets ET2-ZSpec

Ultrakanna

Standardized kanna extracts with published alkaloid content: powders, droplets, capsules and gumdrops. The vendor our readers buy from most.

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Definition:
An alkaloid is a naturally occurring compound found in plants that typically contains nitrogen and has physiological effects on humans or animals.

In the context of kanna:
Kanna (Sceletium tortuosum) contains several key alkaloids — like mesembrine, mesembrenone, and ∆7-mesembrenone — that are responsible for its mood-lifting, calming, and serotonin-regulating effects.

These alkaloids interact with systems in the brain such as:

  • Serotonin reuptake inhibition
  • PDE-4 inhibition
  • VMAT-2 modulation</